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2022 Mercedes-Benz S 500 4MATIC Problems

Owner-reported complaints filed with NHTSA, grouped by component

Data refreshed

Owner complaintsComplaints are reports submitted to NHTSA by owners and drivers. NHTSA does not verify most reports before publishing them, and a complaint does not establish that a defect exists. Volume is influenced by how many of a vehicle were sold, how long it has been on the road, and how much attention an issue has received.
6
Latest Sep 22, 2026
Components namedHow many of our component categories appear on at least one report for this model year. One report can name several.
5
Crash or fire reportedComplaints whose submitter recorded that a crash or a fire occurred. These are the reporter's own answers on the NHTSA form, not verified findings.
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What this page shows

Everything below is an owner-reported complaint submitted to NHTSA about the 2022 Mercedes-Benz S 500 4MATIC, grouped by the component NHTSA recorded on the report. These are not confirmed defects, and they are not recalls. NHTSA does not verify most reports before publishing them, and a category with more reports in it is not evidence that a part is defective.

Complaints are reports submitted by owners and drivers to NHTSA. They are not verified and do not establish that a defect exists.

Reports by component

Ranked by how many owner reports name each component category

  • Driver assistance444.4%
  • Electrical222.2%
  • Airbags111.1%
  • Other / unspecified111.1%
  • Powertrain (other)111.1%

Percentages are of component mentions. A single complaint can name more than one component, so these do not sum to the total complaint count.

Each component in detail

What the reports in each category say, in the owners' own words

Driver assistance

Reports naming forward-collision avoidance, lane keeping, back-over prevention, cruise control and related electronic driver-assistance systems.

4
reports

From owner reports, verbatim

The following pictures will again show the issues that I'm having while driving my 2022 S Class Mercedes, while using the cruise control on the Belt Parkway. It shows me stuck in traffic and, although I can only go 11 miles an hour while I’m stuck in traffic, the cruise control wants to push it to 80 mph, which is indeed VERY VERY DANGEROUS!! as you can well imagine. Also, as you can see in the second picture, I have the cruise control set to 39 MPH. I have been writing for the past two months with no resolve as yet. The repair records speak for themselves and still Mercedes Benz offers no remedy. It would appear that it's going to take a severe accident or fatality to bring some type of action on your part to replace this vehicle, which is definitely a LEMON!!

NHTSA ID 11651654 · filed Mar 31, 2025

Here we go again, while driving on a side road with a 20 mph school speed limit, the cruise control wants to SPEED UP to 60 mph!! WHAT IS IT GOING TO TAKE TO REMEDY THIS BEFORE I’M INVOLVED IN A SERIOUS ACCIDENT!!

NHTSA ID 11650963 · filed Mar 27, 2025

Too few reports in this category for a page of its own — they appear in the full complaint list.

Electrical

Reports naming the electrical system — wiring, battery, charging, control modules, infotainment and electrical accessories.

2
reports

From owner reports, verbatim

I leased my 2022 S 500, Mercedes Benz. on September 28, 2022 and after about a year, I have had issues with the large screen/radio and cruise control in the vehicle. All events are documented at the Rockville Centre, Long Island service center. I have made numerous complaints beginning in January of this year through emails and was assigned a case number with Mercedes Benz corporate which is 12240831. On numerous occasions, while using the cruise control set to 50 MPH, the vehicle will accelerate to  80 MPH  on a highway with a  50 MPH speed limit. Then on other occasions,  while using the cruise control, the vehicle will accelerate to  80 MPH  on a highway with a  25 MPH speed limit. Then,  at other times, while using the cruise control set to 50 MPH, on a highway which has a 50 MPH speed limit, the car will reduce to 10 MPH .  All of these scenarios are  VERY  DANGEROUS  as you can well imagine. On many other occasions, the screen map will become blurry & distorted causing confusion as to my whereabouts. **The time has come for a replacement/repurchase of this vehicle and,  I believe, at this time, this vehicle should be considered for the  "LEMON LAW"  under all applicable State and Federal laws.   I can send a separate email with all of the pictures of the screen and cruise control issues.

NHTSA ID 11649962 · filed Mar 23, 2025

as a loyal Mercedes Benz customer for the past 15 years, here I am writing to you for the fourth time since January 28th. of this year. My case number is [XXX]. I leased my 2022 S 500, VIN # [XXX] on [XXX] and after about a year, I have had issues with the large screen/radio in the vehicle. All events are documented with your Rockville Centre, Long Island service facility where the staff has been very helpful. On numerous occasions, while using the cruise control set to 50 MPH, the vehicle will accelerate to 80 MPH on a highway with a 50 MPH speed limit. Then on other occasions, while using the cruise control, the vehicle will accelerate to 80 MPH on a highway with a 25 MPH speed limit. Then, at other times, while using the cruise control set to 50 MPH, on a highway which has a 50 MPH speed limit, the car will reduce to 10 MPH . All of these scenarios are VERY DANGEROUS as you can well imagine. On many other occasions, the screen map will become blurry & distorted causing confusion as to my whereabouts. On a side note, we had an usually warm day [XXX]. here in New York City of about 55° and while riding around NY City, the air conditioner was not cooling properly and was brought in for service shortly afterwards for that issue as well as all of the screen issues. The same problem with the air conditioning occurred last week as the temperatures in New York City were about 55° and, frustrated again, I brought the vehicle in for the air conditioner and screen issues and they kept the vehicle for ten (10) days!!. **The time has come for a replacement/repurchase of this vehicle and, I believe, at this time, this vehicle should be considered for the "LEMON LAW" under all applicable State and Federal laws. I will be sending a separate email with a few pictures of the screen issues. INFORMATION REDACTED PURSUANT TO THE FREEDOM OF INFORMATION ACT (FOIA), 5 U.S.C. 552(B)(6)

NHTSA ID 11648771 · filed Mar 17, 2025

Too few reports in this category for a page of its own — they appear in the full complaint list.

Airbags

Reports naming the air-bag system — deployment behaviour, inflators, sensors and warning lights.

1
report

From owner reports, verbatim

Left front windows airbag malfunctioned and had to be totally replaced. Airbag shorted internally. Fault code B002111.

NHTSA ID 11766189 · filed Sep 22, 2026

Too few reports in this category for a page of its own — they appear in the full complaint list.

Other / unspecified

Reports whose component NHTSA recorded as unknown, or that do not map to one of the categories above.

1
report

From owner reports, verbatim

The factory upgrade 21 inch spoke wheels with Pirelli P-Zero low profile tires are averaging a blow out every 800 miles. 5 flats and 2 sidewall blisters in the last 10,000 miles. Pirelli P-Zero 255/35/R21 Front and 285/30/R21 Rear are all four available for inspection if you tell me to save them before I replace them. There have been thousands of complaints and law suits re this issue just in the last 5 years on mercedes cars with low profile tires; to Mercedes, Pirelli, through legal discovery, to enthusiasts forums, and to NHTSA My first blowout was at 30 mph hitting a 1 1/2" deep pothole full of rain water. That one blew out the front right and blistered the sideall of the right rear at once. Then one of the new replacements blew on hitting a storm drain set 1" into the pavement on the way home from the dealership. I've been driving 60 years, and never had a single pothole blowout before now. Sidewall tears release all or most of the air at once creating an extremely dangerous situation. Somebody will lose control and hurt or kill someone, or behurt while stopped in an unsafe spot. Since the car can't be towed and has no spare, it is exteremely costly and inconvenient to replace a tire. It has cost me thousands so far, and left my disabled wife and me stranded beside the highway. Car is on a flat and one and a blister on a second tire right now in driveway. Best fix is to go to a square wheel/tire fitment using 19" x 8.5" wheels with 35 offset 66.6 mm bore on all four, all season radials. To keep outside diamter the same for the computer, 255/45/R19 /AS/ XL W and with acoustic tuning or dampening to match the quiet factory tires on these cars. 20" wheels is no good, because to maintain diameter would require the same too short 35 sidewall profile on two of the tires. Staggered 19 inch wheels will work, but the square fitment allows for tire rotaion and for the carrying of a spare. Maybe make that optional for replacement recall.

NHTSA ID 11747686 · filed Jul 1, 2026

Too few reports in this category for a page of its own — they appear in the full complaint list.

Powertrain (other)

Powertrain reports that are not specifically the engine or transmission — driveshafts, axles, transfer cases and differentials.

1
report

From owner reports, verbatim

as a loyal Mercedes Benz customer for the past 15 years, here I am writing to you for the fourth time since January 28th. of this year. My case number is [XXX]. I leased my 2022 S 500, VIN # [XXX] on [XXX] and after about a year, I have had issues with the large screen/radio in the vehicle. All events are documented with your Rockville Centre, Long Island service facility where the staff has been very helpful. On numerous occasions, while using the cruise control set to 50 MPH, the vehicle will accelerate to 80 MPH on a highway with a 50 MPH speed limit. Then on other occasions, while using the cruise control, the vehicle will accelerate to 80 MPH on a highway with a 25 MPH speed limit. Then, at other times, while using the cruise control set to 50 MPH, on a highway which has a 50 MPH speed limit, the car will reduce to 10 MPH . All of these scenarios are VERY DANGEROUS as you can well imagine. On many other occasions, the screen map will become blurry & distorted causing confusion as to my whereabouts. On a side note, we had an usually warm day [XXX]. here in New York City of about 55° and while riding around NY City, the air conditioner was not cooling properly and was brought in for service shortly afterwards for that issue as well as all of the screen issues. The same problem with the air conditioning occurred last week as the temperatures in New York City were about 55° and, frustrated again, I brought the vehicle in for the air conditioner and screen issues and they kept the vehicle for ten (10) days!!. **The time has come for a replacement/repurchase of this vehicle and, I believe, at this time, this vehicle should be considered for the "LEMON LAW" under all applicable State and Federal laws. I will be sending a separate email with a few pictures of the screen issues. INFORMATION REDACTED PURSUANT TO THE FREEDOM OF INFORMATION ACT (FOIA), 5 U.S.C. 552(B)(6)

NHTSA ID 11648771 · filed Mar 17, 2025

Too few reports in this category for a page of its own — they appear in the full complaint list.

Higher-selling and older vehicles accumulate more reports. Counts are not failure rates and are not directly comparable between vehicles that sold in very different numbers.

Elsewhere on this vehicle

Data sources

Data on this page last refreshed .