Engine misfire on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was delivered to Ford of Spartanburg (Ford dealership) for diagnosis. The vehicle is still out of service. Ford's diagnosis, Repair Order 593079, June 26, 2026: "WILL NEED TO REPLACE ALL SPARK PLUGS AND WIRES, WILL ALSO NEED TO REPLACED ALL COILS DUE TO MISFIRES ON ALMOST EVERY CYLINDER." The Ford service advisor wrote the same day: "The engine also has a misfire that is unrelated to the transmission concern." Ford quoted $4,376.35 for the ignition components and wrote: "AFTER REPAIRING TRANSMISSION WILL NEED TO DIAGNOSE ALL OTHER CONCERNS WITH VEHICLE, CANNOT DIAG ANYTHING AT MOMENT DUE TO NOT BEING ABLE TO DRIVE VEHICLE." Ford has not completed the engine diagnosis; on July 27, 2026 it advised against a compression test and offered one at $920.00. This is the second engine failure on this VIN. In January 2024 at 103,177 miles, the same Ford dealership diagnosed "Found a misfire and low compression on cylinder 3, ordered engine and replaced the engine with new intake gaskets, exhaust manifold gaskets, torque converter nuts, found the reinforcement cracked and replaced it" and installed a Ford service engine, part LC3Z-6006-B (Invoice 551352C; I paid $10,000.00). That Ford replacement engine is the one now misfiring, after at least 63,580 miles. Note on mileage: Ford's RO 593079 records 103,778 miles; Ford's own January 2024 invoice recorded 103,177 and independent records show 166,757 on January 12, 2026 and 169,140 on February 4, 2026. The Ford RO figure is not an actual reading. The same 7.3L engine has failed on nine vehicles in this fleet; NHTSA holds VOQ 11582566, 11582592, 11582598, 11582601, 11582604 and ODI 11714692, 11714694, and NHTSA ODI (Mr. J. Williams) has the complete record as of September 6, 2026. North Carolina DOJ Consumer Protection File No. 2026-180591 is open on the same matter.
- NHTSA ID
- 11763935
- Incident
- Feb 13, 2026
Engine failure on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was taken out of service and has not run since. Two diagnoses, both in writing. ACME Mobile Service, July 27, 2026, at 152,760 miles: "Found the #5 cylinder is completely disabled and dropped out. Truck will need a new motor." Ford of Spartanburg (Ford dealership), Repair Order 595835, August 25, 2026: "FOUND ENGINE IS KNOCKING, WILL NEED TO REPLACE MOTOR." Ford quoted $16,000.82 for a long-block replacement. The engine is available for inspection. This is the second engine failure on this VIN. In March 2023 at 83,575 miles the engine was rebuilt with new Ford parts (camshaft, sixteen lifters, rocker arms, cylinder heads) after a camshaft and lifter failure. On the day the rebuild was completed the shop recorded "03/31/2023- NEW ENGINE FAILED. ENGINE STARTED KNOCKING AND HAD NOISE COMING FROM TOP END." and Ford replaced the complete engine under warranty in April 2023 (Ford claim CAS-42271539-G0F3ZF). That Ford replacement engine is the one that has now failed, after 69,185 miles. Ford's own repair order of August 25, 2026 lists Safety Recalls 20S73 and 24S07 for this VIN at $0.00, i.e. not performed, while the vehicle sat at the Ford dealership. Ford Customer Experience declined assistance on August 25, August 28 and September 9, 2026 and closed the case. The same 7.3L engine has failed on nine vehicles in this fleet; NHTSA already holds VOQ 11582566, 11582592, 11582598, 11582601, 11582604 and ODI 11714692, 11714694 on those, and NHTSA ODI (Mr. J. Williams) has the complete vehicle-by-vehicle record as of September 6, 2026. North Carolina DOJ Consumer Protection File No. 2026-180591 is open on the same matter.
- NHTSA ID
- 11763932
- Incident
- Jan 6, 2026
fatal Camshaft and lifter failure requiring an engine replacement
- NHTSA ID
- 11714692
- Incident
- Jul 31, 2024
Engine failure at 78,172, excess wear to the camshaft lobes and valve tappet surface. We have had 22 failures. There was a recall -24B27 for 2021 and 2022 models year for idle oil pressure. Most vans had 70 to 80k on them by the time we received a letter. Some engine have been changed twice. Ford has a serious problem and is not acknowledging it. Please help! Montachusett Regional Transit Authority , Fitchburg MA 01420
- NHTSA ID
- 11701901
- Incident
- Mar 4, 2025
This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.
- NHTSA ID
- 11643148
- Incident
- Jun 1, 2024
This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.
- NHTSA ID
- 11643144
- Incident
- Jul 1, 2024
This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.
- NHTSA ID
- 11643142
- Incident
- Apr 1, 2024
See attached document for complaint,
- NHTSA ID
- 11582604
- Incident
- Feb 23, 2024
See attached document for complaint,
- NHTSA ID
- 11582598
- Incident
- Feb 23, 2024
See attached document for complaint,
- NHTSA ID
- 11582566
- Incident
- Feb 23, 2024
The contact owns a 2021 FORD E-350. The contact received notification of NHTSA Campaign Number: 20V795000 (ENGINE) however, the dealer informed the contact that only one part of the remedy, mentioned on the manufacturer's website, was available and not the other. The contact received the reprogramming (UPDATE THE POWERTRAIN CALIBRATION) mentioned on the Ford website but not the other portion of the repair mentioned on the website (INSTALL ENGINE COVER INSULATION PATCHES IN THE RIGHT HAND AND LEFT HAND INNER LOWER CORNERS OF THE ENGINE COVE). The contact stated that the failure reoccurred and that when they looked up the recall on the NHTSA website stated that there was no recall repair available at all. The contact stated that the manufacturer exceeded a reasonable amount of time for the recall repair. The manufacturer was made aware of the issue. The contact had stated that after they received the repairs regarding this matter their vehicle's engine cover still gets extremely hot. The failure mileage was unknown. Vin tool confirms parts not yet available.
- NHTSA ID
- 11421609
- Incident
- Aug 1, 2020
Higher-selling and older vehicles accumulate more reports. Counts are not failure rates and are not directly comparable between vehicles that sold in very different numbers.