2021 Ford E350

The Office of Defects Investigation (ODI) opened Recall Query (RQ) 24003 on February 27, 2024, to evaluate the scope and remedy effectiveness of NHTSA recall 24V097. On February 16, 2022, Ford Motor Company (Ford) issued a safety recall, NHTSA recall 22V089, for certain 2021-2022 Ford E-350 and E-450 vehicles equipped with dual rear wheels. According to the filing, specific hydraulic lines could leak resulting in a sudden loss of power steering and power brake assist, increasing the risk of a crash. The remedy involved a dealer inspection of the lines and their replacement as necessary. Only vehicles that failed the inspection received updated parts. On February 9, 2024, Ford issued a new recall, NHTSA recall 24V097, to replace the specific hydraulic lines on any vehicle that had not yet been inspected and on any vehicle which had passed inspection within the previous twelve months. However, vehicles which had passed the inspection more than twelve months ago would not be included within the scope of the new recall, as Ford deemed them to have a low likelihood of failure. ODI opened this RQ to better understand Ford's scoping of recall 24V097, specifically concerning the inspected-only vehicles not included in the new recall filing. ODI sent Ford an information request letter on April 18, 2024. Ford responded, in full, on May 31, 2024. ODI reviewed Ford's data which showed that the vehicles not included in the new recall had a predicted failure rate of less than 0.25% within 10 years from the date of inspection. By comparison, the vehicles included in the new filing have had a failure rate of approximately 2% prior to being recalled again. ODI analysis of complaint and warranty data further supports Ford's assessment that vehicles that passed inspection more than twelve months prior to recall 24V097 are unlikely to experience the defect condition. ODI is closing this RQ without a manufacturer action. The closing of this investigation does not constitute a finding by NHTSA that a safety-related defect does not exist. The Agency reserves the right to take additional action if warranted by future circumstances. To review the ODI reports cited in the Opening Resume ODI Report Identification Number document, go to NHTSA.gov.

Engine misfire on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was delivered to Ford of Spartanburg (Ford dealership) for diagnosis. The vehicle is still out of service. Ford's diagnosis, Repair Order 593079, June 26, 2026: "WILL NEED TO REPLACE ALL SPARK PLUGS AND WIRES, WILL ALSO NEED TO REPLACED ALL COILS DUE TO MISFIRES ON ALMOST EVERY CYLINDER." The Ford service advisor wrote the same day: "The engine also has a misfire that is unrelated to the transmission concern." Ford quoted $4,376.35 for the ignition components and wrote: "AFTER REPAIRING TRANSMISSION WILL NEED TO DIAGNOSE ALL OTHER CONCERNS WITH VEHICLE, CANNOT DIAG ANYTHING AT MOMENT DUE TO NOT BEING ABLE TO DRIVE VEHICLE." Ford has not completed the engine diagnosis; on July 27, 2026 it advised against a compression test and offered one at $920.00. This is the second engine failure on this VIN. In January 2024 at 103,177 miles, the same Ford dealership diagnosed "Found a misfire and low compression on cylinder 3, ordered engine and replaced the engine with new intake gaskets, exhaust manifold gaskets, torque converter nuts, found the reinforcement cracked and replaced it" and installed a Ford service engine, part LC3Z-6006-B (Invoice 551352C; I paid $10,000.00). That Ford replacement engine is the one now misfiring, after at least 63,580 miles. Note on mileage: Ford's RO 593079 records 103,778 miles; Ford's own January 2024 invoice recorded 103,177 and independent records show 166,757 on January 12, 2026 and 169,140 on February 4, 2026. The Ford RO figure is not an actual reading. The same 7.3L engine has failed on nine vehicles in this fleet; NHTSA holds VOQ 11582566, 11582592, 11582598, 11582601, 11582604 and ODI 11714692, 11714694, and NHTSA ODI (Mr. J. Williams) has the complete record as of September 6, 2026. North Carolina DOJ Consumer Protection File No. 2026-180591 is open on the same matter.

NHTSA ID

11763935

Incident

Feb 13, 2026

Engine failure on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was taken out of service and has not run since. Two diagnoses, both in writing. ACME Mobile Service, July 27, 2026, at 152,760 miles: "Found the #5 cylinder is completely disabled and dropped out. Truck will need a new motor." Ford of Spartanburg (Ford dealership), Repair Order 595835, August 25, 2026: "FOUND ENGINE IS KNOCKING, WILL NEED TO REPLACE MOTOR." Ford quoted $16,000.82 for a long-block replacement. The engine is available for inspection. This is the second engine failure on this VIN. In March 2023 at 83,575 miles the engine was rebuilt with new Ford parts (camshaft, sixteen lifters, rocker arms, cylinder heads) after a camshaft and lifter failure. On the day the rebuild was completed the shop recorded "03/31/2023- NEW ENGINE FAILED. ENGINE STARTED KNOCKING AND HAD NOISE COMING FROM TOP END." and Ford replaced the complete engine under warranty in April 2023 (Ford claim CAS-42271539-G0F3ZF). That Ford replacement engine is the one that has now failed, after 69,185 miles. Ford's own repair order of August 25, 2026 lists Safety Recalls 20S73 and 24S07 for this VIN at $0.00, i.e. not performed, while the vehicle sat at the Ford dealership. Ford Customer Experience declined assistance on August 25, August 28 and September 9, 2026 and closed the case. The same 7.3L engine has failed on nine vehicles in this fleet; NHTSA already holds VOQ 11582566, 11582592, 11582598, 11582601, 11582604 and ODI 11714692, 11714694 on those, and NHTSA ODI (Mr. J. Williams) has the complete vehicle-by-vehicle record as of September 6, 2026. North Carolina DOJ Consumer Protection File No. 2026-180591 is open on the same matter.

NHTSA ID

11763932

Incident

Jan 6, 2026

fatal Camshaft and lifter failure requiring an engine replacement

NHTSA ID

11714692

Incident

Jul 31, 2024

Engine failure at 78,172, excess wear to the camshaft lobes and valve tappet surface. We have had 22 failures. There was a recall -24B27 for 2021 and 2022 models year for idle oil pressure. Most vans had 70 to 80k on them by the time we received a letter. Some engine have been changed twice. Ford has a serious problem and is not acknowledging it. Please help! Montachusett Regional Transit Authority , Fitchburg MA 01420

NHTSA ID

11701901

Incident

Mar 4, 2025

This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.

NHTSA ID

11643148

Incident

Jun 1, 2024

This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.

NHTSA ID

11643144

Incident

Jul 1, 2024

This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.

NHTSA ID

11643142

Incident

Apr 1, 2024

See attached document for complaint.

NHTSA ID

11623611

Incident

Oct 17, 2024

This article supersedes TSB 25-2572 to update the Parts List to correct the part number LC3Z-6006-L to LC3Z-6781-A, remove the flex plate bolts AL3Z-6379-BA from the parts list as these bolts are in kit LC3Z-6781-A, update the claim quantity of the part number W709771-S440 to 9 pieces (F-650/F750-Engine Replacement), W706447-S437 and W715068-S437 to 4 pieces, W712861-S439 to 8 pieces(F-Super Duty Pickup And Chassis Cab-Engine Replacement) / 8 pieces (F-53 Motorhome/F-59 Stripped Chassis Cab/F-650,F750 Engine Replacement) / W714286-S442 to 4 pieces (F-Super Duty Pickup And Chassis Cab-Camshaft and Tappet Repair / F-Super Duty Pickup And Chassis Cab-Engine Replacement), include LC3Z-6020-A for the Engine replacement lists, include 1 fuel injector seal kit to the Camshaft and Tappet repair lists, include 4 pieces of W520114-S440 to the E Series-Camshaft and Tappet Repair list, and update the engine oil part numbers XO-5W30-Q1SP and CXO-5W30-LSP6. Some of the vehicles listed in the Model statement above may exhibit an upper engine ticking or tapping noise at idle. Customers may also report experiencing ro

Advance Notice – Customer Satisfaction Program 25N17 Certain 2015-2025 Model Year Multiple Vehicle Lines Rear View Camera Replacement If Required After Dealer Evaluation

Some 2021-2026 F-150 vehicles equipped with a 5.0L/5.2L engine, 2021-2025 F-Super Duty/F-53 Motorhome/F59 Commercial Stripped Chassis vehicles equipped with a 6.8L/7.3L engine and 2021-2025 E-Series/F-650/F-750 vehicles equipped with a 7.3L engine may exhibit a rattle/scraping noise upon startup that may remain after the engine is running. Workshop Manual (WSM),

Ford and Lincoln vehicles equipped with wired keyless entry keypad systems and accessory wireless keyless entry keypad systems may or may not come with a wallet card containing the master code. Unlike the integrated wired keypad, the accessory wireless keypad master code cannot be retrieved from the vehicle using a diagnostic scan tool or from the label printed on the body control module (BCM). The Factory Keyless Entry Code application within the diagnostic scan tool will not provide an applicable master code for the accessory wireless keypad. If the wallet card for an accessory keypad is not available, the "Wireless RF Keypad Diagnosis Guide" can be referenced and provides direction on how to retrieve the master code. This guide is located under the Workshop Manual tab > Accessories > Installation > Wireless RF Keypad Diagnosis Guide > PPT C > Step C2.<br /><br /> Note: The only available keypad for some vehicles from the assembly plant is the accessory wireless keyless entry keypad. The integrated wired keypad cannot be installed on vehicles not equipped from the factory with a wired keyless entry k

This article supersedes TSB 25-2322 to update the Service Procedure, Labor Operations and Parts List. Some of the vehicles listed in the Model statement above may exhibit an upper engine ticking or tapping noise at idle. Customers may also report experiencing rough engine performance, engine misfire, or a malfunction indicator lamp (MIL) with diagnostic trouble code (DTC) P0301-P0308 in the powertrain control module (PCM). This may be due to camshaft and/or valve tappet having excess wear within the engine assembly.

This is a proactive investigation program by Ford Motor Company to inspect a limited number of affected vehicles that are customer-owned. Ford is voluntarily conducting this program to evaluate the software currently installed on one or more electronic modules in the affected vehicles.