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2021 GMC Sierra 2500 Engine Problems

Owner-reported complaints naming the engine system, filed with NHTSA

Data refreshed

Engine reportsComplaints are reports submitted to NHTSA by owners and drivers. NHTSA does not verify most reports before publishing them, and a complaint does not establish that a defect exists. Volume is influenced by how many of a vehicle were sold, how long it has been on the road, and how much attention an issue has received.
8
Latest Jun 26, 2026
Share of all reportsThis category as a share of every owner report on file for this model year. One report can name more than one component, so the categories overlap.
16%
of 51 total
Crash or fire reportedReports in this category whose submitter recorded that a crash or a fire occurred. The reporter's own answer on the NHTSA form, not a verified finding.
0
Injuries or deaths reportedTotals the submitters entered on their own reports in this category. Not verified by NHTSA and not a casualty statistic.
0

What this page shows

Reports naming the engine itself — including stalling, misfires, oil consumption, cooling and internal engine components. Every record below is an owner-reported complaint about the 2021 GMC Sierra 2500 submitted to NHTSA — not a confirmed defect, not a recall and not a manufacturer bulletin. 8 reports on file name it.

Complaints are reports submitted by owners and drivers to NHTSA. They are not verified and do not establish that a defect exists.

Owner reports naming engine

Shown in the owner’s own words, exactly as filed

EngineFuel systemPowertrain (other)
Filed Jun 26, 2026

I am reporting repeated failures involving both the transmission and diesel emissions (DEF) system on my 2021 GMC Sierra 2500HD Denali equipped with the 6.6L Duramax diesel engine and Allison 10-speed automatic transmission. While under warranty, the truck required replacement of the aftertreatment fuel injector and later the Reductant Control Module due to DEF/emissions system failures. General Motors also completed recall-related transmission software updates on the vehicle. At approximately 154,833 miles, the transmission began shifting improperly, set transmission fault codes, and required complete replacement at my expense. Less than 5,000 miles later, the vehicle again experienced a "Service DEF System" warning with multiple diagnostic trouble codes. Repairs required replacement of the DEF tank, DEF heater assembly, and NOx sensor. These repeated failures involve major drivetrain and emissions components on a heavy-duty truck. DEF system failures can place the vehicle into reduced-power (derate) mode, limiting vehicle performance and creating potential safety concerns while driving or towing. I am submitting this complaint so these failures can be documented as part of NHTSA's evaluation of similar vehicles.

NHTSA ID
11746749
Incident
Dec 16, 2025
Engine
Filed Apr 1, 2026

The contact owns a 2021 GMC Sierra 2500. The contact stated that while driving at 55 MPH, the vehicle stalled unexpectedly. There were no warning lights illuminated. The vehicle was taken to the local dealer, where it was diagnosed, and determined that the engine needed to be replaced. The engine was replaced; however, the failure recurred. While at a stop and attempting to drive around a curve, the vehicle stalled. No warning lights were illuminated. The vehicle was taken to the local dealer, where it was diagnosed with engine failure. The vehicle was not repaired. The failure mileage was approximately 77,000. The VIN was not available.

NHTSA ID
11728457
Incident
Jan 1, 2023
Mileage
77,000 mi
Engine
Filed Feb 3, 2026

80,000 Miles, complete engine break down. 12,000 to repair

NHTSA ID
11715295
Incident
Jan 26, 2026
EnginePowertrain (other)
Filed Dec 19, 2024

The contact owns a 2021 GMC Sierra 2500. The contact stated while driving 40-55 MPH, the vehicle started losing motive power. The contact stated while pulling into a nearby independent mechanic shop, the vehicle started jerking significantly and stalled midway. The check engine warning light was illuminated. The mechanic diagnosed the vehicle with transmission failure. The vehicle was towed to the residence. The local dealer and several unknown dealers were notified of the failure and informed the contact that the transmission assembly was not available and could not be ordered. The vehicle was towed to CJ's Transmission, where the transmission was taken apart. The mechanic determined that the transmission needed to be replaced. The vehicle was being repaired with a rebuilt transmission. The contact received notification of NHTSA Campaign Number: 24V797000 (Power Train); however, the part to do the recall repair was not yet available. The local dealer was contacted. The contact stated that the manufacturer had exceeded a reasonable amount of time for the recall repair. The manufacturer was made aware of the failure and offered a modest monetary compensation for the repair. The failure mileage was approximately 134,000. Parts distribution disconnect.

NHTSA ID
11631610
Incident
Nov 28, 2024
Mileage
134,000 mi
Driver assistanceElectricalEngine
Filed Aug 15, 2024

Smog system check and Engan warning light keeps come on.

NHTSA ID
11608733
Incident
Aug 13, 2024
Engine
Filed Feb 28, 2024

The contact owns a 2021 GMC Sierra 2500. The contact stated that the vehicle was equipped with an engine block heater that he plugged into the vehicle when the weather was below 32 degrees to start the vehicle. The contact stated that he noticed that the engine block heater was causing the GFCI outlet in his residence, to experience an electrical short circuit. The dealer was notified of the failure and informed the contact that it was a known failure. An appointment was scheduled for diagnostic testing. The vehicle was not diagnosed or repaired. The contact related the failure to NHTSA Campaign Number: 19V328000 (Engine) however, the VIN was not included. The manufacturer was notified of the failure and a case was opened. The failure mileage was approximately 55,000.

NHTSA ID
11574476
Incident
Feb 14, 2024
Mileage
55,000 mi
Engine
Filed May 16, 2022

Diesel Exhaust Fluid tank, high pressure

NHTSA ID
11464852
Incident
Apr 26, 2022
Driver assistanceEngine
Filed Feb 28, 2021

THE TRUCK IS PARKED AT DEALERSHIP

NHTSA ID
11398288
Incident
Feb 24, 2021
Mileage
10 mi

Higher-selling and older vehicles accumulate more reports. Counts are not failure rates and are not directly comparable between vehicles that sold in very different numbers.

Other components reported on this vehicle

Categories with enough reports to have a page of their own

Elsewhere on this vehicle

Data sources

Data on this page last refreshed .