2021 Mercedes-Benz E350 Problems
Owner-reported complaints filed with NHTSA, grouped by component
Data refreshed
What this page shows
Everything below is an owner-reported complaint submitted to NHTSA about the 2021 Mercedes-Benz E350, grouped by the component NHTSA recorded on the report. These are not confirmed defects, and they are not recalls. NHTSA does not verify most reports before publishing them, and a category with more reports in it is not evidence that a part is defective.
Complaints are reports submitted by owners and drivers to NHTSA. They are not verified and do not establish that a defect exists.
Reports by component
Ranked by how many owner reports name each component category
- Electrical422.2%
- Engine422.2%
- Driver assistance316.7%
- Fuel system316.7%
- Powertrain (other)316.7%
- Brakes15.6%
Percentages are of component mentions. A single complaint can name more than one component, so these do not sum to the total complaint count.
Each component in detail
What the reports in each category say, in the owners' own words
Electrical
Reports naming the electrical system — wiring, battery, charging, control modules, infotainment and electrical accessories.
From owner reports, verbatim
Vehicle: 2021 Mercedes-Benz E350 Sedan (W213) VIN: [XXX] While operating the vehicle, the diagnostic system displayed the fault code P240200 related to the Evaporative Emission Control System (EVAP). The warning message indicated a “positive short circuit” in the fuel vapor leak diagnosis pump control circuit. The malfunction appears to involve the EVAP diagnostic module and/or associated electrical wiring near the fuel system. The affected component may be available for inspection upon request. The issue raises safety concerns because the fault involves an electrical short circuit associated with the fuel vapor control system. Potential risks may include electrical overheating, malfunction of the fuel vapor management system, fuel vapor leakage, emissions-related failures, or unexpected vehicle operating issues. Prior to the incident, warning messages appeared on the vehicle diagnostic display. The fault code was identified using the vehicle’s onboard diagnostic system. No collision or fire occurred at this time. The problem has not yet been fully repaired, but preliminary assessment suggests a possible failure of the EVAP leak detection pump, control module, wiring harness, connector, or related electrical components. The condition may be reproducible because the warning message remains active. The vehicle has not yet been inspected by the manufacturer or insurance representatives. Dealer inspection is planned. UNKNOWN whether this condition is currently associated with an official recall or service campaign for this VIN. This vehicle was originally purchased in the United States and is currently located outside the [XXX] . INFORMATION REDACTED PURSUANT TO THE FREEDOM OF INFORMATION ACT (FOIA), 5 U.S.C. 552(B)(6)
1) Rear view camera sometimes working, some times not working. (Message reads “system inoperative “ 2) Forward view camera also affected. 3) display shown “12V battery low in battery “ 4) Not long ago, just had vehicle suddenly vibrating vigorously while backing up from parking and during driving. Gas paddle not responding when stepping down, ( vehicle was then towed to dealer and they updated some kind of electrical thing)
Too few reports in this category for a page of its own — they appear in the full complaint list.
Engine
Reports naming the engine itself — including stalling, misfires, oil consumption, cooling and internal engine components.
From owner reports, verbatim
Engine keeps having a misfire that Mercedes put a TSB out for and once the misfire happen I cause the vehicle to go in a limp mode which causes the vehicle to loose power happened to me in the freeway. The car had 54K miles and Mercedes refused to repair the issue as the engine part failure isn’t common.
My 2021 Mercedes-Benz E350 (VIN [XXX] ) developed a serious engine issue involving cylinder misfire and check engine light. The dealer diagnosed it as a leaking exhaust valve on cylinder 4, related to TSB LI01.30-P-072328, which documents valve seat wear in M260 engines. This is a known defect acknowledged by Mercedes in technical bulletins, and other customers in the U.S. have received warranty extensions or goodwill coverage. I was denied coverage even though this is a manufacturer defect that can lead to misfire, power loss, and potential stalling, posing a safety risk on the road. Mercedes-Benz USA refuses to cover the repair (~$7,600+), even though it relates to a factory-documented problem. I’m requesting that NHTSA investigate this engine defect, as it may qualify for a safety recall or mandatory extended warranty coverage. INFORMATION REDACTED PURSUANT TO THE FREEDOM OF INFORMATION ACT (FOIA), 5 U.S.C. 552(B)(6)
Too few reports in this category for a page of its own — they appear in the full complaint list.
Driver assistance
Reports naming forward-collision avoidance, lane keeping, back-over prevention, cruise control and related electronic driver-assistance systems.
From owner reports, verbatim
1) Rear view camera sometimes working, some times not working. (Message reads “system inoperative “ 2) Forward view camera also affected. 3) display shown “12V battery low in battery “ 4) Not long ago, just had vehicle suddenly vibrating vigorously while backing up from parking and during driving. Gas paddle not responding when stepping down, ( vehicle was then towed to dealer and they updated some kind of electrical thing)
I was parking and the 360 view sensor did not come up. When I tried to back out and move forward again, I realized the back up camera would not come on. I turned the car on and off and then tried again to reverse to engage the camera but was instead given a message that says system inoperative.
Too few reports in this category for a page of its own — they appear in the full complaint list.
Fuel system
Reports naming fuel storage or delivery — tanks, pumps, lines, injectors and fuel leaks.
From owner reports, verbatim
Vehicle: 2021 Mercedes-Benz E350 Sedan (W213) VIN: [XXX] While operating the vehicle, the diagnostic system displayed the fault code P240200 related to the Evaporative Emission Control System (EVAP). The warning message indicated a “positive short circuit” in the fuel vapor leak diagnosis pump control circuit. The malfunction appears to involve the EVAP diagnostic module and/or associated electrical wiring near the fuel system. The affected component may be available for inspection upon request. The issue raises safety concerns because the fault involves an electrical short circuit associated with the fuel vapor control system. Potential risks may include electrical overheating, malfunction of the fuel vapor management system, fuel vapor leakage, emissions-related failures, or unexpected vehicle operating issues. Prior to the incident, warning messages appeared on the vehicle diagnostic display. The fault code was identified using the vehicle’s onboard diagnostic system. No collision or fire occurred at this time. The problem has not yet been fully repaired, but preliminary assessment suggests a possible failure of the EVAP leak detection pump, control module, wiring harness, connector, or related electrical components. The condition may be reproducible because the warning message remains active. The vehicle has not yet been inspected by the manufacturer or insurance representatives. Dealer inspection is planned. UNKNOWN whether this condition is currently associated with an official recall or service campaign for this VIN. This vehicle was originally purchased in the United States and is currently located outside the [XXX] . INFORMATION REDACTED PURSUANT TO THE FREEDOM OF INFORMATION ACT (FOIA), 5 U.S.C. 552(B)(6)
The engine is misfiring and not powering correctly during driving. Car is failing to take off and today almost caused an accident due to the car would not pull off from the traffic light with oncoming traffic due to loss of power. Safety was at risk due to an accident was almost caused due to car not moving in on coming traffic Dealership is citing that is needs to have a cylinder replaced but will not tell me why it needs to be replaced, why this has happened or what could have been done pre maintenance to avoid this issue Check engine light came on Dealer has been contacted, and was told this is a common issue for this to happen to newer cars, but will not fix the issue and extended warranty will not cover due to this is a manufacturer issue
Too few reports in this category for a page of its own — they appear in the full complaint list.
Powertrain (other)
Powertrain reports that are not specifically the engine or transmission — driveshafts, axles, transfer cases and differentials.
From owner reports, verbatim
Engine misfires, lower engine power, and a lit check engine/Malfunction Indicator Lamp. Mercedes-Benz issued an Emission Service Campaign (No. 2021070006, internal code 21P1590208) to replace out-of-spec ignition coils on 657 vehicles from model year 2021, including the E-Class. My VIN was not included in the recall campaign but my vehicle is experiencing these exact symptoms as referenced in the first sentence. My vehicle has 48,000 miles.
With the car only have about 15,000 miles the transmission has failed . I have seen there have been recalls of other models with similar complaints of transmission failure .
Too few reports in this category for a page of its own — they appear in the full complaint list.
Brakes
Reports naming service brakes, the antilock braking system, brake hoses, master cylinders or the parking brake.
From owner reports, verbatim
The contact owns a 2021 Mercedes-Benz E350. The contact stated that while parking the vehicle the emergency brake independently seized. The contact stated that the vehicle abruptly stopped. The vehicle would not drive forward or backward. The contact contacted the dealer and a service technician was dispatched to the location. The service technician connected the vehicle to the diagnostic equipment. The contact was advised that the vehicle was not safe to drive. The vehicle was towed to the dealer where it was diagnosed with a failed brake caliber voltage malfunction and the brake caliber voltage needed to be replaced. The vehicle was repaired. The manufacturer was made aware of the failure. The failure mileage was approximately 24,001.
Too few reports in this category for a page of its own — they appear in the full complaint list.
Higher-selling and older vehicles accumulate more reports. Counts are not failure rates and are not directly comparable between vehicles that sold in very different numbers.
Elsewhere on this vehicle
Data sources
- NHTSA Office of Defects Investigation — owner-reported complaints and the components recorded on them
Data on this page last refreshed .