2025 Lexus IS

The contact owns a 2025 Lexus IS-350. The contact stated that the vehicle was purchased brand new. The contact stated that within four days of driving the vehicle, the contact started to experience health and safety issues that persisted throughout the time the vehicle was driven, and the contact noticed an abnormal odor coming from the vehicle. The contact experienced extremely swollen abdomen causing severe digestive distress, constipation, diarrhea and loss of appetite. The contact experienced swollen lymph nodes on the left side of the groin, abnormal weight gain, debilitating fatigue, insomnia, loss of breath, reduced eyesight, loss of strength, joints pain, reduced cognitive ability, malaise. Additionally, the contact experienced hair loss that stopped once the contact stopped driving the vehicle in the month of June. The contact sought medical assistance, and the lab work showed low level of iron. The vehicle was taken to the dealer, and the dealer was informed of the issue. The dealer performed a detailing of the vehicle to resolve the issue; however, the contact continued to experience the symptoms while driving the vehicle. The contact hired Nal East Environmental Services(2021 Bridgetown Pike, Feasterville-Trevose, PA 19053) to perform a test on the vehicle. The test was performed, and the contact was informed that extremely positive levels of Volatile Organic Compound(VOC) was found on the vehicle. The manufacturer was notified of the issue, and the Doctor's letter, stating that the VOC presence in the vehicle had made the contact sick, was sent to the manufacturer; however, no assistance was provided. The vehicle was not repaired. The failure mileage was 15.

NHTSA ID

11687952

Incident

Sep 17, 2025

Mileage

15 mi

OBSOLETE NOTICE February 2, 2026: This bulletin is now obsolete. Please see L-SB-0004-26.

Some 2018 – 2025 model year Lexus vehicles equipped with the Enform™ 2.0 Navigation System, require a Special Service Tool (SST) USB flash drive to update the map, points of interest, and system software.

Some 2005 – 2026 Lexus vehicles that have undergone water intrusion may exhibit a condition in which a musty odor is present. Follow the procedures in this bulletin to remediate the odor and address this condition. The purpose of this Service Bulletin is to provide general guidelines and procedures for odor remediation. This Service Bulletin provides a guide on how to prepare and treat the interior of the vehicle for odor remediation. Refer to the applicable model and model year Repair Manuals and the EPA (Environmental Protection Agency) website for the most up-to-date safety and precautionary guidelines. This Service Bulletin is to provide a general overview and direction for the odor remediation process.

Some customers may experience operational difficulties with some telematics features which they cannot resolve on their own. These resources, in conjunction with the Repair Manual, are for dealership personnel to assist those customers with user issues, user errors, and compatibility issues with other vehicle systems and external applications encountered while operating telematics features.

Some 2016 – 2020 model year GS F, 2008 – 2014 model year IS F, 2022 – 2025 model year IS 500, 2018 – 2025 model year LC 500, 2021 – 2025 model year LC 500c, and 2015 – 2025 model year RC F vehicles with 2UR-GSE engines may exhibit a MIL ON condition with one or more of the following Diagnostic Trouble Codes (DTCs): •P0505 – Idle Control System •P2111 – Throttle Actuator Control System – Stuck Open The throttle body assembly with motor and ventilation hoses no. 2 and no. 3 have been modified to address these conditions.

The air conditioning dye injection tool kit has been developed to aid in identifying the location of air conditioning refrigerant leaks. The procedures outlined in this Service Bulletin aid in locating, inspecting, and repairing refrigerant leaks.